However, reps for both stars have flat out denied that Segel and Holmes, who broke off from Cruise and Scientology in 2012, are an item.
If they had indeed dated, that would have made Holmes the second starlet with whom Segel has hooked up.
Many critics and audiences agreed that Holmes had given her best performance in the film as April.
Variety said it was "one of her best film performances." "Each actor shines", wrote Elvis Mitchell, "even Ms.
Holmes had a small role (six and one-half minutes of screen time) as Hannah Green, the talented student who lusts after Professor Grady Tripp (Douglas's character, who is her instructor and landlord).
"It was very difficult for me to leave Wilmington, to have my little glass bubble burst and move on. On the other hand it was refreshing to play someone else", she said in 2004.
Holmes' first starring role post-Dawson's Creek was in 2003's Pieces of April, a gritty comedy about a dysfunctional family on Thanksgiving.
She first achieved fame for her role as Joey Potter on The WB television teen drama Dawson's Creek from 1998 to 2003.
She appeared in the 1998 thriller Disturbing Behavior, which won her an MTV Movie Award for Best Breakthrough Performance.